Cord blood is rich in hematopoietic (blood-forming) stem cells
It contains valuable, therapeutic stem cells
- Unrestricted somatic stem cells (USSC)
The discovery of unrestricted somatic stem cells (USSC), a non-hematopoietic stem cell population, brought cord blood (CB) to the forefront of regenerative medicine, a new field that uses cord blood to repair damaged tissues and organs.
- Mesenchymal stem cells (MSC)
Mesenchymal stem cells are multipotent stem cells that can differentiate into a variety of cell types, such as osteoblasts (bone cells), chondrocytes (cartilage cells) and adipocytes (fat cells) and more.
- Endothelial progenitor cells (EPC)
The use of human cord-blood-derived EPCs is quite attractive for induction of angiogenesis in critically ischemic diseases.
It has been successfully used to treat many types of life-threatening diseases
Stem cells have been used to treat many types of malignant and non-malignant life-threatening diseases. Cord blood stem cells have saved the lives of over forty thousand patients worldwide.
It has been recommended that transplanting cord blood stem cells with a perfect HLA match should be the first choice over bone marrow to treat malignant diseases (Smith A. and Wagner J. BJH147, 246–261, 2009).
It has been used in clinical trials to repair damaged tissues and organs, and the outcomes have been promising
With advances in research on cord blood and clinical trials, it has shown promising outcomes in repairing damaged tissues and organs for treatment of diabetes, heart disease, liver disease, spinal cord injury, brain injury and more.
Autologous transplantation of cord blood could become an important therapy
- It is increasing much faster than allogeneic transplantation
The rising rate of autologous therapy (treatment with the baby’s own cord blood stem cells) exceeds exponential growth, compared with linear growth in the number of allogeneic cord blood transplants being performed (NMDP) since 2006 (treatment with cord blood stem cells donated by others) (Verter F and Nietfeld J. Cytotherapy Vol.12 Supplement 1, 2010 (abstract)).